These two pictures show body scans of two women approximately the same age and height. The one on the left weighs 113 kg (250 lbs), while the one on the right weighs 54 kg (120 lbs). Accumulated adipose tissue is not the only difference between the two; the obese woman has an enlarged heart and her lungs are somewhat restricted.
This is where an obese person may see excess intracellular breakdown from all of the inflammatory cytokines that are reproduced by the increase adipose tissue. This excessive cellular breakdown can potentially lead to further diseases of the organs, possibly even lead to the formation of a cancerous lesion.
Obesity has recently been declared a disease by the American Medical Association. While this does not have any legal ramifications, it may encourage doctors and insurance companies to take more steps in treating and preventing obesity. However, not everyone agrees with the AMA’s definition, citing that obesity is a complex issue with multiple causes and treatment options.
Obesity is defined as having a body mass index over 30 kg/m^2. It greatly increases the risk of Type 2 diabetes, heart disease, and osteoarthritis.
More info: http://bbc.in/14whyV6